PUBLICATION
2022
88. I. J. Moon, H. K. Yoon, D. Kim, M. E. Choi, S. H. Han, J. H. Park, S. W. Hong, H. Cho, D.-k. Lee, and C. H. Won, Efficacy of Asymmetric siRNA Targeting Androgen Receptors for the Treatment of Androgenetic Alopecia. Molecular Pharmaceutics, AOP (2022) (IF=5.364)
87. S. Ren, S. Cho, R. Lin, V. Gedi, S. Park, C. W. Ahn, D.-k. Lee, M.-h. Lee, S. Lee, and S. Kim, Nonbiodegradable Spiegelmer-Driven Colorimetric Biosensor for Bisphenol a Detection. Bionsensors 12, 864 (2022) (IF=5.423)
86. Y. G. Kang, J. Kim, K. Lee, J. Y. Choe, P. Dua, and D. K. Lee*, Retinoic Acid-Inducible Gene I-Mediated Innate Immune Stimulation by Chemically Synthesized Long Double-Stranded RNAs Is Structure and Sequence Dependent. Nucleic Acid Ther 32, 321-332 (2022) (IF=5.486)
2020
85. J. Y. Choe, D. S. Son, Y. Kim, , J.-k. Lee, H. Shin, W. J. Kim, Y. G. Kang, P. Dua, S. W. Hong, J. H. Park, and D.-k. Lee*, L-Type Calcium Channel Blocker Enhances Cellular Delivery and Gene Silencing Potency of Cell-Penetrating Asymmetric siRNAs. Mol Pharm 17, 777-786 (2020) (IF=3.610)
2019
84. H.-s. Shin, V. Gedi, J.-k. Kim, and D.-k. Lee*, Detection of Gram-negative bacterial outer membrane vesicles using DNA aptamers. Sci Rep 9, 13167 (2019) (IF=4.011)
83. H.-s. Shin, S. B. Jung, S. Park, P. Dua*, and D.-k. Lee*, ALPPL2 is a Potential Diagnostic Biomarker for Pancreatic Cancer Derived Extracellular Vesicles. Mol Ther Methods Clin Dev 15, 204-210 (2019) (IF=4.875)
82. Y. G. Kang, J. Y. Choe, S. Lee, J. Hwang, H. Lim, J. Lee, and D.-k. Lee*, Tripodal RNA with 3' Overhangs Prevents RIG-I mediated Innate Immune Response. Nucleic Acid Ther 29, 291-299 (2019) (IF=3.780)
2018
81. M. Kwak, I. Jung, Y. G. Kang, D.-k. Lee, S. Park*, Multi-block magnetic nanorods for controlled drug release modulated by Fourier transform surface plasmon resonance. Nanoscale, 10(39), 18690-18695 (2018) (IF=7.233)
80. S. Hyun, Y. Choi, H. N. Lee, C. Lee, D. Oh, D.-k Lee, C. Lee*, Y. Lee*, J. Yu*, Construction of histidine-containing hydrocarbon stapled cell penetrating peptides for in vitro and in vivo delivery of siRNAs. CHEM SCI 9, 3820-3827 (2018) (IF=8.668)
79. P. Dua*, S. Kang, H. Shin, S. Kim, and D.-k. Lee*, Cell-SELEX based identification of a human and mouse cross-reactive endothelial cell-internalizing aptamer. Nucleic Acid Ther 28, 262-271 (2018) (IF=2.338)
78. Y. Kim, Y. G. Kang, J. Y. Choe, D. Lee, C. Shin, S. W. Hong*, and D.-k. Lee*, RNA interference-mediated gene silencing by branched tripodal RNAs does not require Dicer processing. Nucleic Acid Ther 28, 44-49 (2018) (IF=2.338)
2017
77. S. Sajeesh, J. Y. Choe, and D.-k. Lee*, Core-Shell Hybrid Nanostructured Delivery Platforms for Advanced RNAi Therapeutics, Nanomed J 12, 2271-2286 (2017) (IF=4.727)
2016
76. J. Hwang, C. Chang, J. H. Kim, C. T. Oh, H. N. Lee, C. Lee, D. Oh, C. Lee, B. Kim, S. W. Hong, and D.-k. Lee*, Development of Cell-Penetrating Asymmetric Interfering RNA Targeting Connective Tissue Growth Factor. J Invest Dermatol 136, 2305-2313 (2016) (IF=7.216)
75. P. Dua, S. Ren, S. W. Lee, J.-k. Kim, H.-s. Shin, O.-c. Jeong, S. Kim*, and D.-k Lee*, Cell-SELEX Based Identification of an RNA Aptamer for Escherichia coli and Its Use in Various Detection Formats. Mol Cells 39, 807-813 (2016) (IF=2.090)
2015
74. V. Loczenski Rose, S. Shubber, S. Sajeesh, S. G. Spain, S. Puri, S. Allen, D.-k. Lee, G. S. Winkler*, and
G. Mantovani*, Phosphonium Polymethacrylates for Short Interfering RNA Delivery: Effect of Polymer and RNA Structural Parameters on Polyplex Assembly and Gene Knockdown. Biomacromolecules 16, 3480-3490 (2015) (IF=5.750)
73. S. W. Hong#, J. W. Yoo#, S. Bose#, J. H. Park, K. Han, S. Kim, C. Y. Lim, H. Kim*, and D.-k. Lee*,
Understanding the molecular aspects of oriental obesity pattern differentiation using DNA microarray.
J Transl Med 13, 331 (2015) (IF=3.930;SCIE)
72. P. Dua, S. Sajeesh, S. Kim, and D.-k. Lee*, ALPPL2 aptamer-mediated targeted delivery of 5-fluoro-2'-deoxyuridine to pancreatic cancer. Nucleic Acid Ther 25, 180-186 (2015) (IF=2.929)
71. S. Sajeesh, and D.-k. Lee*, Advanced therapeutic platforms based on Non-Classicaltripodal interfering RNA structural format. RNA & DISEASE 2, e708 (2015) (IF=Pending)
70. S. Sajeesh, J. Y. Choe, T. Y. Lee, and D.-k. Lee*, Guanidine modified polyethyleneimine-g-polyethylene glycol nanocarriers for long interfering RNA (liRNA) based advanced anticacner therapy. J Mater Chem B 3, 207-216 (2015) (IF=4.726)
2014
69. S. Sajeesh, T. Y. Lee, J. K. Kim, D. S. Son, S. W. Hong, S. H. Kim, W. S. Yun, S. Kim, C. I. Chang, C. Li, and D.-k. Lee*, Efficient intracellular delivery and multiple target gene silencing triggered by tripodal interfering RNA-based nanoparticles: a promising approach in liver-specific RNAi delivery. J Control Release 196, 28-36 (2014) (IF=7.261)
68. J. H. Park#, S. W. Hong#, S. Yun, D.-k. Lee*, and C. Shin*, Effect of an siRNA with asymmetric RNA/dTdT overhang on RNA interference activity. Nucleic Acid Ther 24, 364-371 (2014) (IF=2.914)
67. S. Ren, Y. Jiang, H. R. Yoon, S. W. Hong, D. Shin, S. Lee, D.-k. Lee, M. M. Jin, I. M. Min, and S. Kim*, Label-free detection of the transcription initiation factor assembly and specific inhibition by aptamers. Bull Kor Chem Soc 35, 1279-1284 (2014) (IF=0.835)
66. J. Park, S. Bose, S. W. Hong, D.-k. Lee, J. W. Yoo, C.Y. Lim, M. Lee, and H. Kim*, Impact of GNB3-C825T, ADRB3-Trp64Arg, UCP2-3'UTR 45bp del/ins, and PPARgamma-Pro12Ala polymorphisms on Bofutsushosan response in obese subject: a randomized, double-blind, placebo-controlled trial. J Med Food 17, 558-570 (2014) (IF=1.699)
65. H. S. Kang, J. Kim, H. J. Lee, B. M. Kwon, D.-k. Lee, and S. H. Hong*, LRP-dependent pepsin clearance induced by 2'-hydroxycinnamaldehyde attenuates breast cancer cell invasion. Int J BIochem Cell BIol 53, 15-23 (2014) (IF=4.240)
64. S. W. Hong#, J. H. Park#, S. Yun, C. H. Lee, C. Shin*, and D.-k. Lee*, Effect of the guide strand 3'-end structure on the gene silencing potency of asymmetric siRNA. Biochem J 461, 427-434 (2014) (IF=4.779)
63. S. Sajeesh#, T. Y. Lee#, S. W. Hong, P. Dua, J. Y. Choe, A. Kang, W. S. Yun, C. Song, S. H. Park, S. Kim, C. J. Li, and D.-k. Lee*, Long dsRNA-mediated RNA interference and immunostimulation: A targeted delivery approach using polyethyleneimine based nano-carriers. Mol Pharm. 11, 872-884 (2014) (IF=4.787;SCIE)
62. S. W. Hong, Y. Jiang, S. Kim, C. J. Li, and D.-k. Lee*, Target gene abundance contributes to the efficiency of siRNA-mediated gene silencing. Nucleic Acid Ther 24, 192-198 (2014) (IF=2.914)
2013
61. T. Y. Lee#, C. I. Chang#, D. Lee, S. W. Hong, C. Shin, C. Li, D. Haussecker, S. Kim, and D.-k. Lee*, RNA interference-mediated simultaneous silencing of four genes using cross-shaped RNA. Mol Cells 35, 320-326 (2013) (IF=2.178)
60. P. Dua, H. S. Kang, S. M. Hong, M.-S. Tsao, S. Kim, and D.-k. Lee*, Alkaline phosphatase ALPPL2 is a novel pancreatic carcinoma-associated protein. Cancer Res 73, 1934-1945 (2013) (IF=8.23) [Highlighted in Cancer Research as breaking advances (link)]
59. E. H. Park, S. Kim, J. Y. Jo, S. J. KIm, Y. Hwang, J.-M. Kim, S.-Y. Song, D.-k. Lee, and S. S. Koh*, Collagen triple helix repeat containing-1 promotes pancreatic cancer progression by regulating migration and adhesion of tumor cells. Carcinogenesis 34, 694-702 (2013) (IF=5.4)
58. C. Chang, S. W. Hong, P. Dua, S. Kim, and D.-k. Lee*, The design, preparation, and evaluation of asymmetric small interfering RNA for specific gene silencing in mammalian cells. Method Mol Biol 942, 135-152 (2013)
2012
57. L. Ghisolfi, X. Hu, A.C. Keates, D.-k. Lee, and C. J. Li*, Ionizing radiation induces stemness in cancer cells. PLos One 7, e43628 (2012) (SCIE: IF=4.41)
56. S. Some, S. M. Ho, P. Dua, E. Hwang, Y. H. Shin, H. Yoo, J. S. Kang, D.-k. Lee, and H. Lee*, Dual functions of highly potent graphene derivative-Poly-l-Lysine composites to inhibit bacteria and support human cells. ACS Nano 6, 7151-7161 (2012) (IF=9.86)
55. X. Hu, L. Ghisolfi, A. C. Keates, J. Zhang, S. Xiang, D.-k. Lee, and C. J. Li*, Induction of cancer cell stemness by chemotherapy. Cell Cycle 11, 2691-2698 (2012) (SCIE: IF=5.0)
54. S. W. Hong, J. W. Yoo, J. H. Park, S. Bose, H.-J. Kim, S. Kim, and D.-k. Lee*, Gene expression profiling of Bangpungtongseong-san (Bofutsushosan) and Bangkihwangki-tang (Boiogito) administered individuals. Biochip J 6, 139-148 (2012) (SCIE: IF=0.87)
53. V. Tarallo, Y. Hirano, B. D. Gelfand, S. Dridi, N. Kerur, Y. Kim, W. G. Cho, H. Kaneko, B. J. Fowler, S. Bogdanovich, R. J. C. Albuquerque, W. W. Hauswirth, V. A. Chiodo, J. F. Kugel, J. A. Goodrich, S. L. Ponicsan, G. Chaudhuri, M. P. Murphy, J. L. Dunaief, B. K. Ambati, Y. Ogura, J. W. Yoo, D.-k. Lee, P. Provost, D. R. Hinton, G. Nunez, J. Z. Baffi, M. E. Kleinman, and J. Ambati*, DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88. Cell 149, 847-859 (2012) (IF=32.4)
52. C. I. Chang, T. Y. Lee, S. Kim, X. Sun, S. W. Hong, J. W. Yoo, P. Dua, H. S. Kang, S. Kim, D. Lee, C. Shin, C. J. Li, and D.-k. Lee*, Enhanced intracellular delivery and multi-target gene silencing triggered by tripodal RNA structures. J Gene Med 14, 138-146 (2012) (IF=3.08)
51. C. I. Chang#, T. Y. Lee#, J. W. Yoo, D. Shin, M. Kim, S. Kim, and D.-k. Lee*, Branched, tripartite-interfering RNAs silence multiple target genes with long guide strands. Nucl Acid Ther 22, 30-39 (2012) (IF=2.986)
2011
50. S.-g. Jo#, S. W. Hong#, J. W. Yoo, C. H. Lee, S. Kim, S. Kim, and D.-k. Lee*, Selection and optimization of asymmetric siRNA targeting human c-MET gene. Mol Cells 32, 543-548 (2011) (IF=2.046)
49. J. W. Yoo, S. W. Hong, S. Bose, H. Kim, S. Y. Kim, S. Kim, and D.-k. Lee*, The role of transglutaminase in double-stranded DNA-triggered antiviral innate immune response. Bull Kor Chem Soc 32, 3893-3898 (2011) (IF=0.871)
48. P. Dua, J. W. Yoo, S. Kim, and D.-k. Lee*, Modified siRNA structure with a single nucleotide bulge overcomes conventional siRNA-mediated off-target silencing . Mol Ther 19, 1676-1687 (2011) (IF=7.149) [featured article]
47. C. I. Chang#, T. Y. Lee#, P. Dua, S. Kim, C. J. Li, and D.-k. Lee*, long dsRNA-mediated RNA interference and immunostimulation: long interfering RNA (liRNA) as a potent anticancer therapeutics. Nucl Acid Ther 21, 149-155 (2011) (IF=2.986)
46. P. Dua#, K. N. Chaudhari#, C. H. Lee, N. K. Chaudhari. S. W. Hong, J.-S. Yu*, S. Kim*, and D.-k. Lee*, Evaluation of toxicity and gene expression changes triggered by oxide nanoparticles. Bull Kor Chem Soc 32, 2051-2057 (2011) (IF=0.871)
45. C. I. Chang#, H. Andrade#, P. Dua, S. Kim, C. J. Li, and D.-k. Lee*, Structural diversity repertoire of gene silencing siRNAs. Nucl Acid Ther 21, 125-131 (2011) (IF=2.986)
44. M. Jo, J. Lee, J.-Y. Ahn, S. Lee, S. W. Hong, J.-W. Yoo, P. Dua, D.-k. Lee*, S. Hong*, and S. Kim*, Development of single-stranded DNA aptamers for specific bisphenol A detection. Oligonucleotides 21, 85-91 (2011) (IF=2.986)
43. J. Y. Ahn, M. Jo. P. Dua, D.-k. Lee, and S. Kim*, A sol-gel-based microfluidics system enhances the efficiency of aptamer selection. Oligonucleotides 21, 93-100 (2011) (IF=2.986)
42. H. Kaneko, S. Dridi, V. Tarallo, B. J. Fowler, B. D. Gelfand, W. G. Cho, M. E. Kleinman, S. L. Ponicsan, W. W. Hauswirth, V. A. Chiodo, K. Karikó, J. W. Yoo, D.-k. Lee, M. Hadziahmetovic, Y. Song, G. Chaudhuri, F. W. Buaas, R. E. Braun, D. R. Hinton, Q. Zhang, H. E. Grossniklaus, J. M. Provis, M. C. Madigan, A. H. Milam, N. L. Justice, R. J. C. Albuquerque, A. D. Blandford, S. Bogdanovich, Y. Hirano, J. Witta, E. Fuchs, D. R. Littman, B. K. Ambati, C. M. Rudin, M. M. W. Chong, P. Provost, J. Kugel, J. A. Goodrich, J. L. Dunaief, J. Z. Baffi, J. Ambati*, Dicer dysregulation induces cytotoxic Alu RNA accumulation in age related macular degeneration. Nature 471, 325-330 (2011) (IF=36.101)
41. P. Dua, S. Kim*, and D.-k. Lee*, Nucleic acid aptamers targeting cell surface proteins. Methods 54, 215-225 (2011) (IF=4.527)[invited review]
40. J. Lee, M. Jo, T. H. Kim, J.-Y. Ahn, D.-k. Lee, S. Kim*, and S. H. Hong*, Aptamer sandwich-based carbon nanotube sensors for single-carbon-atomic-resolution detection of non-polar small molecular species. Lab Chip 11, 52-26 (2011) (IF=6.260)
~ 2010
39. J.-Y. Ahn, S. W. Lee, H. S. Kang, M. Jo, D.-k. Lee*, T. Laurell*, and S. Kim*, Aptamer microarray mediated capture and MS identification of biomarker in serum samples. J Proteome Res 9, 5568-5573 (2010) (IF=5.132)
38. S. Mishra, S. Kim*, and D.-k. Lee*, Recent patents on nucleic acid-based antiviral therapeutics. Rec Pat Anti-infect Drug Disc 5, 255-271 (2010) [review]
37. X. Li#, J. W. Yoo#, J. H. Lee, Y. S. Hahn, S. Kim, and D.-k. Lee*, Identification of sequence features that predict competition potency of siRNAs. Biochem Biophys Res Commun 398, 92-97 (2010) (IF=2.548)
36. P. Dua#, S. Jeong#, S. W. Hong, S. E. Lee, S. Kim*, and D.-k. Lee*, Evaluation of toxicity and gene expression changes triggered by quantum dots. Bull Kor Chem Soc 31, 1555-1560 (2010) (IF=0.936)
35. D.-k. Lee*, S. Kim, A. Keates, and C. J. Li*, Asymmetric RNA duplexes as next generation RNAi inducers. Gene silencing: Theory, Techniques and Applications in press [invited book chapter]
34. S. W. Hong, J. W. Yoo, H. Kim, S. Jeon, S. Bose, S. Kim, and D.-k. Lee*, Evaluation of RNA amplification method for high density DNA microarray. Biochip J 4, 70-74 (2010) (SCIE, IF=1.840)
33. B. G. Han, J. W. Cho, Y. D. Cho, S. Y. Kim, H. J. Yoon, H. K. Song, H. K. Cheong, Y. H. Jeon, D.-k. Lee, S. Lee*, B. I. Lee*, Expression, purification and biochemical characterization of the N-terminal regions of human TIG3 and HRASLS3 proteins. Protein Expr Purif 71, 103-107 (2010) (IF=1.563)
32. S.W. Hong, S. M. Hong, J. W. Yoo, Y. C. Lee, S. Kim, J. T. Lis, and D.-k. Lee*, Phosphorylation of the RNA polymerase II C-terminal domain by TFIIH kinase is not essential for transcription of Saccharomyces cerevisiae genome.Proc Natl Acad Sci USA 106, 14276-14280 (2009) (IF=9.38) F1000-post-publication peer review(교과부 R&D 대표우수성과)
31. H. S. Kang, Y. M. Huh, S. Kim*, and D.-k. Lee*, Isolation of RNA aptamers targeting HER2-overexpressing breast cancer cells using Cell-SELEX. Bull Kor Chem Soc 30, 1827-1831 (2009) (IF=1.257)
30. C. I. Chang, H. S. Kang, C. Ban, S. Kim, and D.-k. Lee*, Dual-target gene silencing by using long, synthetic siRNA duplexes without triggering antiviral responses. Mol Cells 27, 689-695 (2009) (IF=2.023)
29. S.-m. Park#, J. Ahn#, M. Jo, D.-k. Lee, J. Lis*, H. Craighead*, and S. Kim*, Selection and elution of aptamers using nanoporous sol-gel arrays with integrated microheaters. Lab Chip 9, 1206-1212 (2009) (IF=6.478)
28. C. I. Chang, J. W. Yoo, S. W. Hong, S. E. Lee, H. S. Kang, X. Sun, H. A. Rogoff, C. Ban, S. Kim, C. J. Li, and D.-k. Lee*, Asymmetric shorter-duplex siRNA structures trigger efficient gene silencing with reduced non-specific effects. Mol Ther 17, 725-732 (2009) (IF=5.970) [featured article]
27. M. Jung, E. Kim, D.-k. Lee*, and S. Kim*, Comparison of two in vivo models for evaluation of B52 function. Biochip J 3, 50-56 (2009) (SCIE; IF=0.650)
26. S. W. Hong#, M. Jung#, E. Kim, D.-k. Lee*, and S. Kim*, Identification of B52-dependent gene expression signature and alternative splicing using a D. melanogaster B52-null mutant. Bull Kor Chem Soc 4, 323-326 (2009) (IF=1.257)
25. S. W. Hong#, J. W. Yoo#, H. S. Kang, S. Kim, and D.-k Lee*, HIF-1alpha dependent gene expression program during the nucleic acid-triggered antiviral responses. Mol Cells 27, 243-250 (2009) (IF=2.023)
24. H. K. Moon, C. I Chang, D.-k. Lee* and H. C. Choi*, The nuclease effect on the cellular internalization of single walled carbon nanotubes functionalized with fluorescent tag-labeled DNA. Nano Research 1, 351-360 (2008) [cover paper]
23. P. Dua, S. Kim, and D.-k. Lee*, Patents on SELEX and therapeutic aptamers. Recent Pat DNA Gene Seq 2, 172-186 (2008) Review [most accessed articles]
22. J. Ahn, M. Cho, S. Lee, J. Park, S. Hong, S. Shin, M. Jeong, D.-k. Lee, and S. Kim*, Sol-gel material optimization for aptamer biosensors. Mol Cell Toxicol 4, 100-105 (2008) (SCIE)
21. J. W. Yoo, S. Kim, and D.-k. Lee*, Competition potency of siRNA is specified by the 5'-half sequence of the guide strand. Biochem Biophys Res Commun 367, 78-83 (2008) (IF=2.855)
20. J.-a. Kwon#, H. Lee#, K. N. Lee, K. Chae, S. Lee, D.-k. Lee, and S. Kim*, High diagnostic accuracy of antigen microarray for sensitive detection of hepatitis C virus infection. Clin Chem 54, 424-428 (2008) (IF=5.454)
19. S. W. Hong, S. Kim, and D.-k. Lee*, The role of Bach2 in nucleic acid-triggered antiviral innate immune responses. Biochem Biophys Res Commun 365, 426-432 (2008) (IF=2.855)
18. C. I. Chang, S. W. Hong, S. Kim, and D.-k. Lee*, A structure-activity relationship study of siRNAs with structural variations. Biochem Biophys Res Commun 359, 997-1003 (2007) (IF=2.855)
17. S. Lee#, Y. S. Kim#, M. Jo#, M. Jin, D.-k. Lee*, and S. Kim*, Chip-based detection of Hepatitis C virus using RNA aptamers that specifically bind to HCV core antigen. Biochem Biophys Res Commun 358, 47-52 (2007) (IF=2.855)
16. T. Ryu, J. Jung, S. Lee, H. J. Nam, S. W. Hong, J. W. Yoo, D.-k. Lee, and D. Lee*, bZIPDB: a database of regulatory information for human bZIP transcription factors. BMC Genomics 8, 136 (2007) (SCIE; IF=4.029)
-15. S. W. Hong, H. J. Choi, Y. Lee, and D.-k. Lee*, Construction of an RNase P ribozyme library for functional genomics applications. Genomics and Informatics 5, 6-9 (2007)
14. D. Kim, E. Kim, J. Kim, K. M. Park, K. Baek, M. Jung, Y. H. Ko, W. Sung, H. S. Kim, J. H. Suh, C.G. Park, O. S. Na, D.-k. Lee, K. E. Lee, S. S. Han, and K. Kim*, Direct Synthesis of Polymer Nanocapsules with a Noncovalently Tailorable Surface. Angew Chem Int Ed Engl 46, 3471-3474 (2007) (IF=10.232)
13. J. W. Yoo#, S. W. Hong#, S. Kim, and D.-k. Lee*, Inflammatory cytokine induction by siRNAs is cell type- and transfection reagent-specific. Biochem Biophys Res Commun 347, 1053-1058 (2006) (IF=3.0)
12. K. Lee, K. H. Kim, J. A. Kwon, S. Y. Yoon, C. K. Lee, Y. Cho, S. Kim, D.-k. Lee , M. Sohn, and K. N. Lee Serologic Markers of Viral Hepatitis of Korea University Medical Center Patients. Korean J Lab Med 25, 61-65 (2005)
11. D.-k. Lee , Y. Kim, J.-S. Kim and W. Seol, Induction and characterization of a taxol-resistance phenotype with transiently expressed artificial transcription activator libraries. Nucleic Acids Res 32, e116 (2004) (IF = 6.575)
10. D.-k. Lee , J. W. Park, Y.-J. Kim, J. Kim, Y. Lee, J. Kim, and J.-S. Kim, Toward a functional annotation of the human genome using artificial transcription factors , Genome Res 13, 2708-2716 (2003) (IF = 9.635)
9. K.-S. Park # , D.-k. Lee #, H. Lee, Y. Lee, Y.-S. Jang, Y. Kim, H.-Y. Yang, S.-I. Lee, W. Seol, and J.-S. Kim, Phenotype alteration of eukaryotic cells using randomized artificial transcription factor libraries , Nat Biotechnol 21, 1208-1214 (2003) (* equal contribution ) (IF = 17.721)
8. H. Kim, D.-k. Lee , J.-W. Choi, J.-S. Kim, S. C. Park, and H. D. Youn, Analysis of the effect of aging on the response to hypoxia by cDNA microarray , Mech Ageing Dev 124, 941-949 (2003). (IF = 3.214)
7. S. Kim, H. Shi, D.-k. Lee and J. T. Lis, Specific SR protein-dependent splicing substrates identified through genomic SELEX , Nucleic Acids Res 31, 1955-1961 (2003) (IF = 6.575)
6. K.-H. Bae, Y. D. Kwon, H.-C. Shin, M.-S. Hwang, E.-H. Ryu, K.-S. Park, H.-Y. Yang, D.-k. Lee , Y. Lee, J. Park, H.-S. Kwon, H.-W. Kim, B.-I. Yeh, H.-W. Lee, S. H. Sohn, J. Yoon, W. Seol, and J.-S. Kim, Human zinc fingers as modular building blocks in the construction of artificial transcription factors , Nat Biotechnol 21, 275-280 (2003) (IF = 17.721)
5. D.-k. Lee , W. Seol and J.-S. Kim, Custom DNA-binding proteins and artificial transcription factors , Curr Top Med Chem 3, 645-657 (2003) Review (SCIE)
4. D.-k. Lee , S. Kim and J. T. Lis, Different upstream transcriptional activators have distinct coactivator requirements , Genes Dev . 13, 2934-2939 (1999) (IF = 17.013)
3. D.-k. Lee and J. T. Lis, Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo, Nature 393, 389-392 (1998) (IF = 30.979)
2. D.-k. Lee , B. S. Kim, D.-H. Kim, S. Kim, J. H. Chung, D. M. Han, B. L. Lee, and Y. Lee, Expression of an insect antifungal protein of Tenebrio molitor in Escherichia coli. , Mol Cells 5, 429-435 (1995) (IF = 1.128)
1. Y. H. Jung, B. Y. Park, D.-k. Lee , Y. Hahn, J. H. Chung, D. M. Han, H. J. Moon, B. L. Lee and Y. Lee, Biochemical and molecular characterization of an antifungal protein from Tenebrio molitor larvae , Mol Cells 5, 287-292 (1995) (IF = 1.128)