Department of Chemistry
Republic of Korea
Welcome to BMTL
We are working on RNA-based molecular tools for genomics, diagnostics, and therapeutics.
1. Development of novel siRNA structures for functional genomics and therapeutics
The efficiency and specificity of siRNA-based gene silencing made it as a favored tool for functional genomics and as a promising therapeutics.
We are challenging to the development of RNAi therapeutics and specific silencing of genes in research.
2. Nucleic acid aptamers for diagnostic and therapeutic applications
Aptamers are short, single-stranded oligonucleotides which have high affinity and specificity to target.
We are working with SELEX to isolate nucleic acid aptamers against a variety of disease related targets.
News & Publication
"Guanidine modified polyethyleneimine-g-polyethylene glycol nanocarriers for long interfering RNA (liRNA) based advanced anticancer therapy"
S. Sajeesh et al.
J. Mater. Chem. B,
3 (2015) 207–216